Two of the most popular trekking regions are the Everest and Annapurna where many different trails can be followed while the other popular treks are in the Langtang and Kanchenjunga regions. The most challenging is the Great Himalayan Trails, an extensive trail system that covers Nepal from Humla and Darchula in the west to Kanchenjunga in the east. The diversity of trekking trails in Nepal cannot be found in any other part of the world. In fact, the lowest point in Nepal is 59 m above sea-level in the Tarai region while the highest point is Everest, 8,848 m above sea-level, the two points being only 200 kilometres apart as the crow flies. A majority of visitors to Nepal come in via the Tribuvan International Airport in Kathmandu. It is in Kathmandu that trekkers need to acquire their permits and other documentation, either from a trekking agent or from the appropriate offices. These documents will be checked along the trekking route. For those with little time on their hands, there are half-day hikes from Kathmandu to witness breathtaking Himalayan views.

Trekking in Nepal today is completely different from that of the 1960s. In all the main trekking areas, the National Parks and Conservation Areas lodges have been established where trekkers can find accommodation, food and meet other trekkers and locals along the way. A majority of the trails are well maintained and in many cases are sign-posted.

The lodges are well appointed and have facilities for charging batteries and the larger villages often have email facilities. The length, the difficulty and timing of the treks vary greatly and to add to that once outside of the main trekking areas, transport becomes more problematic and often involves at least two journeys made on domestic scheduled flights. Many treks in Nepal begin with a domestic flight to the starting point and many are in remote areas with no road access. Several days of trekking is required to reach the higher mountain areas from the local centers of population and administration.

Nepal has six distinct and diverse vegetation zones ranging from Tropical below a 1,000 m through Sub-tropical 100m – 200m, Lower Temperate 1,700 m – 2,700 m, Upper Temperate 2,400 m – 3,000 m, Sub-alpine 3,000 m – 4,000 m and Alpine 4,000 m to the snowline, above the snowline it is a Himalaya tundra like wilderness. The higher altitudes are home to the elusive Snow leopard, Himalayan Thar, Musk deer and other rare species.

Although the popular treks in Kanchenjunga, Everest, Manaslu, Annapurna are able to provide lodge accommodation, the less frequented treks in those areas and also in other areas west of Annapurna will generally require camping style trek support.